A patient was refused entry into a liver transplant program as doctors thought she had alcoholism. Tests revealed her bladder produced alcohol on its own.
A 61-year-old woman in Pennsylvania who registered for a liver transplant caused a stir after her urine tests were detected many times by the doctors and she assured her not to drink a drop of alcohol.
Of course, doctors at the University of Pittsburgh School of Medicine and Medical Center did not believe the patient’s claims. Because drinking too much alcohol can harm the liver, and instead of a liver transplant, they will have to move the patient to an alcohol dependence treatment program.
According to the Washington Post, the woman had pledged that she was not addicted to alcohol and indeed she did not show any signs of alcoholism when she was not drinking any drops of alcohol during the follow-up.
Finally, doctors discovered that the real problem lies in the production of urine in the bladder. This internal organ made its own wine.
This is the same study published in the journal Annals of Internal Medicine on Monday.
Doctors believe that the woman has a self-generating syndrome of alcohol – a very rare syndrome – that causes the bladder to be full of alcohol.
The huge amount of alcohol does not enter the bloodstream and urine is not present in the presence of ethyl glucuronide or ethyl sulfate, two substances produced when the body metabolizes alcohol.
But the woman’s urine was high in sugar and the yeast Candida glabrata – the two main ingredients for fermenting alcohol. Candida glabrata (the yeast that the body produces and accumulates when this woman eats a lot of sugar) is similar to the yeast Saccharomyces cerevisiae – a type of brewer’s yeast used to convert carbohydrates into wine.
According to Kenichi Tamama, representative of the research team, the patient has diabetes and cirrhosis.
The doctors were surprised and shocked. At first, clinicians thought that patients were dishonest about revealing alcohol use,” Kenichi said.
After pinpointing the cause of a patient’s high alcohol content not due to alcoholism, doctors put the unnamed woman on a liver transplant waiting list.
The case of this woman shows that the assessment of liver transplant cases is very complicated. Existing alcohol monitoring tests have ignored the signs of autogenesis, requiring new standardized guidelines.